Florence Solari is a CRHC, HDR researcher at INSERM, working at the INMG/MeLiS Institute in Lyon (CNRS UMR 5284 - INSERM U1314). For over 20 years, her research has explored various aspects of aging, spanning physiological, metabolomic, cellular, and molecular mechanisms, by leveraging the model organism C. elegans.
Her earlier work was pivotal in uncovering the connection between the oncosuppressive function of PTEN, the second most frequently mutated tumor suppressor, and its role in regulating metabolism and aging. This link was later found to be conserved in mammals.
More recently, Solari’s research has focused on understanding muscle aging, employing genetics, omics, biochemical techniques, microscopy, and systematic AI-driven analysis. Her later work highlights the importance of temporal and tissue-specific regulation of aging and lifespan.
She served on the INSERM Specialists Commission for "Cell Biology, Developmental Biology, and Aging" (2012-2016) and is currently a member of the ARC Passerelle Committee, as well as the Scientific Advisory Board of the RESTORE Aging Institute in Toulouse.
