Bertrand Friguet is full professor of biology at Sorbonne Université, Paris, France. He has been heading the « Biological adaptation and ageing » department at the Institute of Biology Paris Seine (Sorbonne Université, CNRS, INSERM) from 2014 until 2024. He was graduate student of the Ecole Normale Supérieure of Cachan and he got his PhD in Biochemistry in 1987 at the Université Pierre et Marie Curie and the Institut Pasteur of Paris. He was visiting associate in Dr. Earl Stadtman laboratory at NIH, Bethesda, Maryland (1993-1994) and junior member at the Institut Universitaire de France (1995-2000).
During the EU Framework Programme 5, he coordinated the Shared Cost Action Protage on "The role of proteasome in human ageing" (2000-2003). He was then partner of the EU Projects Zincage (2004-2007), Proteomage (2006-2011), Mark-Age (2008-2014) and MyoAge (2009-2014). He has been recently partner of the INSERM Cross-Cutting Program on Ageing "AgeMed" (2017-2023) and the Leducq Foundation Transatlantic Network "Redox regulation of cardiomyocyte renewal" (2018-2023).
The major focus of his research has been to elucidate the role of protein oxidative modification and redox homeostasis as well as oxidized protein degradation and repair during cellular ageing and in oxidative stress situations leading to accelerated ageing with relevant cellular models and model organisms. So far, he is author of 170 papers referenced in PubMed with a total of 13,115 citations and a h-index of 63 (Scopus on 04/02/2025), and inventor in 6 patents.
He has co-founded the OxiProteomics company in 2014. He has recently been listed among the”300 Top-Ranked Scientific Contributors to Gerontology”: https://doi.org/10.1093/gerona/glac129. He is member of the editorial boards of Free Radicals in Biology and Medicine, Redox Biology and Mechanisms of Ageing and Development, editor-in-chief of the journal Biochimie since 2021 and member of the scientific societies SFBBM, ASBMB, SFRR-Europe.
